Wednesday, December 9, 2009

Open access Autism 10K genome-scan data set in NIH GEO

The Affymetrix 10K genome-scan data set from the Autism Genome Project is available in the NIH GEO repository (open access):

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6754

"This is a large linkage study undertaken by The Autism Genome Project (AGP) Consortium to search for candidate genes underlying the etiology of autism. 1168 Muliplex families (= 2 affected individuals) consisting of 7600 individuals were genotyped using Affymetrix 10K whole genome mapping arrays. Copy number analysis was performed using DNA Chip (dChip) Analyzer."

Something just didn't seem right: noticing the unexpected!

The secret of good data analysis is noticing those things that just don't seem right!:

'Wildlife Conservation Officer Cory Bentzoni noticed something suspicious on a Luzerne County highway -- a pickup truck with a heaping pile of doughnuts, breads and pastries spilling over its bed.

"Being that we were so close to bear season, seeing that person drive by with an unusual amount of pastries was like watching an individual go down a row of parked vehicles testing each handle to see if it were open," Bentzoni said in a written statement. "Something just didn't seem right."'

http://www.post-gazette.com/pg/09343/1019403-454.stm

Monday, December 7, 2009

The R Inferno

Here is the link to a PDF file entitled "The R Inferno", which is not only an excellent guide to efficient and good programming practice in R, but is also very funny:

http://www.burns-stat.com/pages/Tutor/R_inferno.pdf

Here's the Abstract:

"If you are using R and you think you’re in hell, this is a map for you."

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Pittsburgh, PA, United States